Cluster III: Syntheses of and with Phosphorus-Containing Compounds

This cluster is primarily concerned with research into underlying structural and reactive properties as well as theoretical issues in phosphorus chemistry. This reflects the formally possible oxidation states, which for phosphorus range from −3 to +5, the extraordinarily high structural diversity of phosphorus compounds. As a central element in achiral and chiral ligands for organometallic and coordination chemistry catalytic processes, phosphorus plays a unique role in catalysis research and as a reagent in organic syntheses. This is also true for some areas of industrial chemistry, mainly in the manufacture of fine chemicals, which often have a high added value. In addition, phosphorus-based organocatalysts are gaining increasing importance.


Neue Organokatalysatoren und kooperative Katalysatorsysteme für die stoffliche Nutzung von CO2 (Dr. T. Werner) (BMBF, 2010-2015)

Selektive Oligomerisierung von Ethylen mit P-N-Liganden-Systemen (Prof. Dr. U. Rosenthal) (SABIC, Linde AG, 2006-2015)

Anschubprojekte im Rahmen der Förderung des Leibniz-WissenschaftsCampus Phosphorforschung Rostock (WGL, 04/2017-06/2019)

Graduiertenschule: Leibniz-WissenschaftsCampus Phosphorforschung Rostock (WGL, 04/2015-03/2019)

KataPlasma: Hydroformylierung mit homogenen Katalysatoren geträgert auf Plasma funktionalisierten Materialien* (BMBF, 06/2016 – 05/2019)



Hülsewede, D.; Meyer, L.-E.; von Langermann, J. (2019): Application of in situ-Product Crystallization and Related Techniques in Biocatalytic Processes. Chemistry - A European Journal 25: 4871-4884, DOI: 10.1002/chem.201804970

Longwitz, L.; Werner, T. (2019): Recent advances in catalytic Wittig-type reactions based on P(III)/P(V) redox cycling. Pure and Applied Chemistry 91 [1]: 95-102, DOI: 10.1515/pac-2018-0920


Felgenhauer, P.; Labbow, R.; Schulz, A.; Villinger, A. (2018): Synthesis and Characterization of Silylated Phosphonium [P(OSiMe3)4]+ and Phosphate [O2P(OSiMe3)2]− Salts. Inorganic Chemistry 57 (15: 9348–9353, DOI: 10.1021/acs.inorgchem.8b01323

Longwitz, L.; Steinbauer, J.; Spannenberg, A.; Werner, T. (2018): Calcium-Based Catalytic System for the Synthesis of Bio-Derived Cyclic Carbonates under Mild Conditions. ACS Catalysis 8: 665-672, DOI: 10.1021/acscatal.7b03367

Schulz, A.; Bresien, J.; Hinz, A.; Villinger, A. (2018): As-N and As-N-P Cage Compounds Generated by [2+2] Addition of Diazenes and Diphosphenes to Diarsadiazanediyls. Eur. J. Inorg. Chem. 10.1002/ejic.201800109, DOI: 10.1002/ejic.201800109


Boeck, G.; Peppel, T.; Selent, D.; Schulz, A. (2017): Chemie in Rostock heute. Nachrichten aus der Chemie 65 [10]: 1030-1033, DOI: 10.1002/nadc.20174062644

Büttner, H.; Steinbauer, J.; Wulf, C.; Dindaroglu, M.; Schmalz, H.-G.; Werner, T. (2017): Organocatalyzed Synthesis of Oleochemical Carbonates from CO2 and Renewables. ChemSusChem 10 [6]: 1076-1079, DOI: 10.1002/cssc.201601163

Hinz, A.; Labbow, R.; Rennick, C.; Schulz, A.; Goicoechea, J.M. (2017): HPCO—A Phosphorus-Containing Analogue of Isocyanic Acid. Angewandte Chemie Internationale Edition 56 [14]: 3911-3915, DOI: 10.1002/anie.201700368

Hoehne, M.; Joksch, M.; Konieczny, K.; Mueller, B.H.; Spannenberg, A.; Peulecke, N.; Rosenthal, U. (2017): Selective Reductions of N,N-Bis{chloro(aryl)- phosphino}-amines Yielding Three-, Five-, Six-, and Eight-Membered Cyclic Azaphosphanes. Chemistry - A European Journal 23 [18]: 4298-4309, DOI: 10.1002/chem.201605836

Müller, B.H.; Konieczny, K.; Höhne, M.; Spannenberg, A.; Peulecke, N.; Moritz, J.O.; Winterberg, M.; Rosenthal, U. (2017): Synthesis of 1,2,4-triaza-3,5-diphospholidines. Monatshefte für Chemie - Chemical Monthly 1-7, DOI: 10.1007/s00706-017-2082-x

Rosenthal, U., Höhne, M., Müller, B.H., Peulecke, N., Spannenberg, A., Jiao, H. (2017): Highly Selective Chromium(0) Mediated Insertion of Nitriles into a Non-polar P-P Bond of a Substituted Hexahydro-1,4-Diaza-2,3,5,6-Tetraphosphorine. European Journal of Inorganic Chemistry, DOI: 10.1002/ejic.201700634

Schulz, A.; Bresien, J.; Hinz, A.; Suhrbier, T.; Thomas, M.; Villinger, A. (2017): Dichloro-cycloazatriphosphane — the missing link between N2P2 and P4 ring systems in the systematic development of NP chemistry. Chemistry - A European Journal 23 [59]: 14738–1474.

Steinbauer, J.; Longwitz, L.; Frank, M.; Epping, J.; Kragl, U.; Werner, T. (2017): Immobilized bifunctional phosphonium salts as recyclable organocatalysts in the cycloaddition of CO2 and epoxides. Green Chemistry 19: 4435-4445, DOI: 10.1039/C7GC01782K

Steinbauer, J.; Werner, T. (2017): Poly(ethylene glycol)s as Ligands in Calcium-Catalyzed Cyclic Carbonate Synthesis. ChemSusChem 10 [15]: 3025-3029, DOI: 10.1002/cssc.201700788


Adam, R.; Alberico, E.; Baumann, W.; Drexler, H.-J.; Jackstell, R.; Junge, H.; Beller, M. (2016): NNP-type pincer imidazolylphosphine ruthenium complexes: Efficient Base-Free Hydrogenation of Aromatic and Aliphatic Nitriles under Mild Conditions. Chemistry - A European Journal 22: 4991-5002, DOI: 10.1002/chem.201504709

Adam, R.; Bheeter, C.B.; Jackstell, R.; Beller, M. (2016): A Mild and Base-Free Protocol for the Ruthenium- Catalyzed Hydrogenation of Aliphatic and Aromatic Nitriles with Tridentate Phosphine Ligands. ChemCatChem 8: 1329-1334, DOI: 10.1002/cctc.201501367

Bläsing, K., Ellinger, S., Harloff, J., Schulz, A., Sievert, K., Täschler, C., Villinger, A., Zur Täschler, C. (2016): Lewis Acid Catalyzed Synthesis of Cyanidophosphates. Chemistry - A European Journal 22 (12: 4175–4188, DOI: 10.1002/chem.201504523

Bresien, J., Faust, K., Hering-Junghans, C., Rothe, J., Schulz, A., Villinger A. (2016): Synthetic strategies to bicyclic tetraphosphanes using P1, P2 and P4 building blocks. Dalton Transactions - The international journal for inorganic, organometallic and bioinorganic chemistry 05/2016:, DOI: 10.1039/C5DT02757H

Büttner, H.; Grimmer, C.; Steinbauer, J.; Werner, T. (2016): Iron-based binary catalytic system for the valorization of CO2 into bio-based cyclic carbonates. ACS Sustainable Chemistry and Engineering 4 [9]: 4805-4814.

Hinz, A., Kuzora, R., Rölke, A.-K., Schulz, A., Villinger, A., Wustrack, R. (2016): Synthesis of a Silylated Phosphorus Biradicaloid and Its Utilization in the Activation of Small Molecules. European Journal of Inorganic Chemistry, DOI: 10.1002/ejic.201600321

Hinz, A.; Rothe, J.; Schulz, A.; Villinger, A. (2016): Reduction of dichloro(diaza-phospha)stibanes – isolation of a donor-stabilized distibenium dication. Dalton Transactions - The international journal for inorganic, organometallic and bioinorganic chemistry 45: 6044-6052, DOI: 10.1039/C5DT02711J

Hinz, A.; Schulz, A.; Villinger, A. (2016): Synthesis of Heavy Cyclodipnictadiphosphanes [ClE(μ-P-Ter)]2 [E = P, As, Sb, or Bi; Ter = 2,6-bis(2,4,6-trimethylphenyl)phenyl]. Inorganic Chemistry 55: 3692–3699, DOI: 0.1021/acs.inorgchem.6b00218

Jungk, P., Täufer, T., Thiel, I., Hapke, M. (2016): Synthesis of Chiral Indenylcobalt(I) Complexes and Their Evaluation in Asymmetric [2+2+2] Cycloaddition Reactions. Synthesis 48 [13]: 2026-2035, DOI: 10.1055/s-0035-1560433

Leibniz ScienceCampus Phosphorus Research Rostock (2016): Phosphorus 2020 - Challenges for Synthesis, Agriculture and Ecosystems. Conference Proceedings of the 8th International Phosphorus Workshop (IPW8), 12.-16.09.2016, Rostock, DOI: 10.12754/procs-2016-i

Pews-Davtyan, A.; Jackstell, R.; Spannenberg, A.; Beller, M. (2016): Zwitterionic phosphonium ligands: synthesis, characterization and application in telomerization of 1,3-butadiene. Chemical Communications 52: 7568-7571, DOI: 10.1039/C6CC02747D

Rodrigues, C., Delolo, F.G., Ferreira, L. M., da S. Maia, P.I., Deflon, V.M., Rabeah, J,, Brückner, A., Norinder, J., Börner, A., Bogado, A.L.; Batista, A.A. (2016): Ruthenium(III)/phosphine/pyridine complexes applied in the hydrogenation reactions of polar and apolar double bonds. Journal of molecular structure 1111: 84-89.

Schirmer, M.-L., Adomeit S., Spannenberg, A., Werner, T. (2016): Novel Base-Free Catalytic Wittig Reaction for the Synthesis of Highly Functionalized Alkenes. Chemistry - A European Journal 22: 2458-2465.

Schirmer, M.-L., Jopp, S., Holz, J., Spannenberg, A., Werner, T. (2016): Organocatalyzed Reduction of Tertiary Phosphine Oxides. Advanced Synthesis & Catalysis 358: 26-29.

Schirmer, M.-L., Spannenberg, A., Werner, T. (2016): Highly functionalized alkenes produced from base-free organocatalytic Wittig reactions: (E)-3-benzyl-idenepyrrolidine-2,5-dione, (E)-3-benzyl-idene-1-methyl-pyrrolidine-2,5-dione and (E)-3-benzyl-idene-1-tert-but-ylpyrrolidine-2,5-. Acta Cryst C72: 504-508, DOI: 10.1107/S2053229616008159

Tenhumberg, N., Büttner, H., Schäffner, B., Kruse, D., Blumenstein, M., Werner, T. (2016): Cooperative Catalyst System for the Synthesis of Oleochemical Cyclic Carbonates from CO2 and Renewables. Green Chemistry, DOI: 10.1039/C6GC00671J


Bresien, J., Faust, K., Schulz, A., Villinger, A. (2015): Low-Temperature Isolation of the Bicyclic Phosphinophosphonium Salt [Mes*2P4Cl][GaCl4]. Angewandte Chemie Internationale Edition 54: 6926 – 693.

Bresien, J., Schulz, A., Villinger, A. (2015): A Tricyclic Hexaphosphane. Chemistry - A European Journal 21 [51]: 18543-1854, DOI: 10.1002/chem.201503808

Brückner, A., Hinz, A., Priebe, J. B., Schulz, A., Villinger, A. (2015): Cyclic Group 15 Radical Cations. Angewandte Chemie Internationale Edition 54 [25]: 7426–7430, DOI: 10.1002/anie.201502054

Büttner, H., Steinbauer, J.,Werner, T. (2015): Synthesis of cyclic carbonates from epoxides and CO2 using bifunctional one-component phosphorus-based organocatalysts. ChemSusChem 8: 2655–2669, DOI: 10.1002/cssc.201500612

Großeheilmann,J., Büttner, H., Kohrt, C., Kragl, U., Werner, T. (2015): Recycling of phosphorus-based organocatalysts by organic solvent nanofiltration. ACS Sustainable Chemistry and Engineering 3: 2817–2822, DOI: 10.1021/acssuschemeng.5b00734

Haerzschel, S.; Kuehn, F.; Woehl, A.; Mueller, W.; Al-Hazmi, M.H.; Alqahtani, A.M.; Mueller, B.H.; Peulecke, N.; Rosenthal, U. (2015): Comparative study of new chromium-based catalysts for the selective tri- and tetramerization of ethylene. Catalysis Science & Technology 5: 1678-1682, DOI: 10.1039/C4CY01441C

Hinz, A., Schulz, A., Villinger, A. (2015): A Mixed Arsenic–Phosphorus Centered Biradicaloid. Angewandte Chemie Internationale Edition 54: 668-672, DOI: 10.1002/anie.201408639

Hinz, A., Schulz, A., Villinger, A. (2015): P–P sigma-bond activation by gold(I) coordination. Chemical Communications 51: 1363-1366, DOI: 10.1039/C4CC09164G

Hoffmann, M., Deshmukh, S., Werner, T. (2015): Scope and Limitation of the Microwave-Assisted Catalytic Wittig Reaction. European Journal of Organic Chemistry 4532-4543.

Schirmer, M.-L., Adomeit, S., Werner, T. (2015): First Base-Free Catalytic Wittig Reaction. Organic Letters 17: 3078-3081.

Schirmer, M.-L., Spannenberg, A., Werner, T. (2015): Crystal structure of diethyl (E)-2-[(benzo­furan-2-yl)methyl­idene]succinate. Acta Cryst E71: 0872.

Werner, T., Hoffmann, M., Deshmukh, S. (2015): Phospholane catalyzed Wittig reaction. European Journal of Organic Chemistry 3286-3295.


Banerjee, D., Junge, K., Beller, M. (2014): Cooperative catalysis by palladium and a chiral phosphoric acid: enantioselective amination of racemic allylic alcohols. Angewandte Chemie Internationale Edition 53: 13049-1305, DOI: 10.1002/anie.201405511

Heinig, S.; Wöhl, A.; Müller, W.; Al-Hazmi, M.H.; Müller, B.H.; Peulecke, M.; Rosenthal, U. (2014): Influence of Ph2PN(R)P(Ph)N(R)H (R=c-Hex, iPr) Ligand Substituents, Modifier, and Process Parameters on Reaction Kinetics of a Chromium-based Catalyst for the Selective Trimerization of Ethylene. ChemCatChem 6 [2]: 514–521, DOI: 10.1002/cctc.201300652

Hinz, A., Kuzora, R., Rosenthal, U., Schulz, A., Villinger, A. (2014): Activation of small molecules by phosphorus biradicaloids. Chemistry - A European Journal 20: 14659–1467, DOI: 10.1002/chem.201403964

Werner, T., Büttner, H. (2014): Phosphorous based bifunctional organocatalysts for the addition of CO2 and epoxides. ChemSusChem 7(12&#: 3268-3271, DOI: 10.1002/cssc.201402477R1

Werner, T., Hoffmann, M. (2014): First Enantioselective Catalytic Wittig Reaction. European Journal of Organic Chemistry 2014 (: 6630-6633, DOI: 10.1002/ejoc.201402941

Werner, T., Hoffmann, M., Deshmukh, S. (2014): First Microwave Assisted Catalytic Wittig Reaction. 2014 (: 6873-6876, DOI: 10.1002/ejoc.201403113


Werner, T., Riahi, A.M., Schramm, H. (2011): Phosphonium Salt Catalyzed Addition of Diethylzinc to Aldehydes. Synthesis 2011: 3482-3490.

Prof. Dr. Matthias Beller LIKAT Angewandte Homogenkatalyse
Dr. Jonas Bresien MNF Institut für Chemie, Anorganische Chemie
Prof. Dr. Marko Hapke LIKAT Cycloadditionen und Übergangsmetallkatalyse
Dr. Christian Hering-Junghans LIKAT Small Molecule Activation
Yuya Hu LIKAT Organokatalyse
Prof. Dr. Udo Kragl MNF Institut für Chemie, Abt. Analytische & Technische Chemie; Technische Chemie
Lars Longwitz LIKAT Organokatalyse
Dr. Dirk Michalik LIKAT Analytik
PD Dr. Hugo Murua Escobar Hämatologie, Onkologie und Palliativmedizin
Dr. Catrin Roolf MED Hämatologie, Onkologie und Palliativmedizin
Prof. Dr. Uwe Rosenthal LIKAT Koordinationschemische Katalyse
Prof. Dr. Axel Schulz MNF Institut für Chemie, Anorganische Chemie
Dr. Jan von Langermann MNF Institut für Chemie, Biokatalyse
Dr. Thomas Werner LIKAT Organokatalyse
Dr. Dana Zimmer IOW Koordinationsbüro P-Campus